Examining Moral Hazard in the Healthcare Insurance Market

This study aims to examine the effect of insurance coverage on medical expenditure in the United States. The data was gathered from the Household Component Medical Expenditure Panel Survey and is a cross-sectional data set with a sample size of approximately 1500 observations. The study also distinguishes between public and private insurance coverage to compare the potential moral hazard in the two separate markets. The results of this study suggest that insurance status, specifically public, has a strong positive effect on healthcare expenditure. This result, combined with a negative relationship between household income and healthcare expenditure, suggests that the source of financial funds rather than the ability to pay determines the demand for healthcare services. The study indicates that individuals are very sensitive to the financial incentives provided by public insurance and inefficiencies within the public insurance market should be examined by future research

Comparing two appraisal models of interest

"Interest is an emotion associated with curiosity, exploration, and knowledge-seeking (Fredrickson, 1998; Izard, 1977; Silvia, 2005a, 2005b, 2006; Tomkins, 1962). The first researchers to propose an appraisal structure of interest were Smith and Ellsworth (1985). An alternative appraisal structure of interest was proposed by Silvia (2005a, 2005b). Experiment 1 tested these competing models. Participants viewed copies of calming and disturbing classical and contemporary paintings, rated each picture for appraisals, and reported their experienced interest, pleasantness/enjoyment, and disturbingness. Experiment 2 aimed to replicate the appraisal structures for the emotion of interest and measured viewing time. Results showed (1) interest and pleasantness were unrelated; (2) novelty-complexity positively predicted interest; (3) disturbing pictures were highly interesting; (4) and viewing time positively predicted interest."--Abstract from author supplied metadata

Back to the future: how future choices impact current satisfaction

Experiment 1 tested whether the number of solutions to a proposed policy that did or did not have a direct impact on participants would influence their current satisfaction. Diverse relative to limited future choices enhanced current satisfaction when they had relevance for participants; there was, however, only a tendency for the number of future choices to influence current satisfaction when the choices did not have relevance for participants. Experiment 2 further explored the influence of choice on satisfaction, tested potential underlying processes, and the influence of individual differences. Results showed that (1) people did not show a preference for diverse over limited relevant choices when the policy had a direct effect on them (relevant condition); (2) when the policy did not have a direct effect (nonrelevant condition), people did not show a preference for diverse over limited options; and (3) participants simulated a future alternative world when considering future choices

Dielectric Replica Measurement : A New Technique for Obtaining the Complex Permittivity of Irregularly Shaped Objects

Dielectric measurements provide valuable information about the properties of materials, and could be used to classify and identify the source of objects in fields such as archaeology. Current methods of identification are all partly destructive, so an innovative electromagnetic method developed by the authors, based on resonant cavity perturbation (RCP), provides an attractive, non-destructive alternative. A problem with traditional RCP is that the changes in frequency and Q-factor vary with the object's shape; however, we overcome this by creating a replica of the object, from a material whose dielectric properties are known. Then, by combining three separate perturbations with orthogonal field directions, due firstly to the object and then to its replica, we eliminate the shape dependency, and thus determine the object's dielectric constant and loss factor. After developing the theory of this novel DRM technique, we demonstrate the principle using a set of geometric shapes made in both polytetrafluoroethylene and a 3D printed material. Further measurements then enable second-order terms to be included in the model, improving its accuracy. Finally, DRM is shown to be capable of distinguishing two irregularly shaped objects of different materials. Potential applications of DRM include determining the provenance of pottery, glasses and flints, and distinguishing ivory from bone. These would be of interest to customs and environmental agencies, as well as museum curators and archaeologists

Bostonia: The Boston University Alumni Magazine. Volume 32

Founded in 1900, Bostonia magazine is Boston University's main alumni publication, which covers alumni and student life, as well as university activities, events, and programs

Mineralisation of soft and hard tissues and the stability of biofluids

Evidence is provided from studies on natural and artificial biofluids that the sequestration of amorphous calcium phosphate by peptides or proteins to form nanocluster complexes is of general importance in the control of physiological calcification. A naturally occurring mixture of osteopontin peptides was shown, by light and neutron scattering, to form calcium phosphate nanoclusters with a core–shell structure. In blood serum and stimulated saliva, an invariant calcium phosphate ion activity product was found which corresponds closely in form and magnitude to the ion activity product observed in solutions of these osteopontin nanoclusters. This suggests that types of nanocluster complexes are present in these biofluids as well as in milk. Precipitation of amorphous calcium phosphate from artificial blood serum, urine and saliva was determined as a function of pH and the concentration of osteopontin or casein phosphopeptides. The position of the boundary between stability and precipitation was found to agree quantitatively with the theory of nanocluster formation. Artificial biofluids were prepared that closely matched their natural counterparts in calcium and phosphate concentrations, pH, saturation, ionic strength and osmolality. Such fluids, stabilised by a low concentration of sequestering phosphopeptides, were found to be highly stable and may have a number of beneficial applications in medicine

The cultural politics of human rights and neoliberalism

Do human rights offer the potential to challenge neo-liberalism? I argue that rather than understanding human rights as ideology, as obscuring or legitimating neo-liberalism, it is more productive to see both human rights and neo-liberalism as hegemonic projects. In this article I explore convergences and divergences between dominant discourses and practices of human rights and neo-liberalism around key ideas ‘the state’, ‘the individual’ and ‘the nation’, to clear a space for appreciation of the cultural politics of human rights: divergences in constructions of responsibility and hierarchies of value of concrete individuals offer openings for challenging ideas and practices of neo-liberalism through campaigns for human rights

VEGFR2 promotes central endothelial activation and the spread of pain in inflammatory arthritis

Chronic pain can develop in response to conditions such as inflammatory arthritis. The central mechanisms underlying the development and maintenance of chronic pain in humans are not well elucidated although there is evidence for a role of microglia and astrocytes. However in pre-clinical models of pain, including models of inflammatory arthritis, there is a wealth of evidence indicating roles for pathological glial reactivity within the CNS. In the spinal dorsal horn of rats with painful inflammatory arthritis we found both a significant increase in CD11b+ microglia-like cells and GFAP+ astrocytes associated with blood vessels, and the number of activated blood vessels expressing the adhesion molecule ICAM-1, indicating potential glio-vascular activation. Using pharmacological interventions targeting VEGFR2 in arthritic rats, to inhibit endothelial cell activation, the number of dorsal horn ICAM-1+ blood vessels, CD11b+ microglia and the development of secondary mechanical allodynia, an indicator of central sensitization, were all prevented. Targeting endothelial VEGFR2 by inducible Tie2-specific VEGFR2 knock-out also prevented secondary allodynia in mice and glio-vascular activation in the dorsal horn in response to inflammatory arthritis. Inhibition of VEGFR2 in vitro significantly blocked ICAM-1-dependent monocyte adhesion to brain microvascular endothelial cells, when stimulated with inflammatory mediators TNFa and VEGF-A165a. Taken together our findings suggest that a novel VEGFR2-mediated spinal cord gliovascular mechanism may promote peripheral CD11b+ circulating cell transmigration into the CNS parenchyma and contribute to the development of chronic pain in inflammatory arthritis. We hypothesise that preventing this glio-vascular activation and circulating cell translocation into the spinal cord could be a new therapeutic strategy for pain caused by rheumatoid arthritis

Machining-induced thermal damage in cortical bone: necrosis and micro-mechanical integrity

In bone cutting, the tissue is exposed to necrosis due to temperature elevation, which can significantly influence postoperative results in orthopaedic surgeries. This damage is usually revealed through histological analysis to show the necrotic extent; however, this technique does not capture mechanical damage, which is essential for a full material integrity assessment. Here, with micro-mechanics, it is demonstrated that machining-induced damage in bone extends beyond the necrotic region. Drilling with different conditions was performed on ex-vivo bovine cortical bone, inducing different damage degrees. Micro-pillar compression tests were performed in the machined sub-surface to identify changes in properties and failure modes caused by drilling. It was revealed that at high cutting temperatures, the bone near the machined surface suffers from lower modulus (−42%), strength (−41%) and brittle behaviour, whereas the bulk bone remains undamaged with pristine properties and ductile behaviour. Histology was also performed to evaluate necrosis and, surprisingly, it was found that the brittle and weaker bone layer is more than three times larger when compared to the necrotic layer, clearly showing that the drilling thermo-mechanical effect could affect not only biologically, but also micro-mechanically. Consequently, these results reveal another kind of bone damage that has so far been neglected